It is unknown at this stage how many jobs will go at Parkes but the Community Public Sector Union of NSW (CPSU) said 52 jobs across the Central West would be lost.

It's expected 15 jobs will go at Orange's three TAFE colleges, 15 at Bathurst and 12 positions at Dubbo.

The union said the 52 Central West jobs would also include staff at Parkes, Lithgow, Forbes, Mudgee, Coonabarabran, Coonamble and Lake Cargelligo.

The cuts will affect a range of roles, including staff who work in student enrolments, team leaders, administrators, two air conditioning and facilities officers and a building maintenance worker.

It is understood only library staff will be spared among the union's members.

Union general secretary Stewart Little said they were part of 678 TAFE jobs to be cut across NSW by July.

Mr Little said more jobs in the Central West were under threat from further cuts.

He said the union had been advised of the cuts by TAFE NSW and that 10 per cent of educational support jobs would go.

"[Premier] Gladys Berejiklian and [treasurer] Dominic Perrottet are deliberately dismantling TAFE NSW to ready it for sale," he said.

"They're helpfully trimming it down for future corporate buyers to come in and snap it up in another NSW assets fire sale.

"The union will be fighting these job cuts at every stage.

"TAFE NSW is a vital piece of infrastructure that must remain in public hands, not dismantled for private operators."

However a TAFE NSW spokesperson said the CPSU was "mistaken in their assertions" as consultation was still underway.

"The CPSU has misunderstood the information provided to staff, confusing role changes for job losses," they said.

"There are no plans to privatise TAFE NSW.

"We have been transparent with employees and unions, these teams would go through organisational design as part of the One TAFE modernisation reforms. These changes will reduce duplication and management layers."

They said changes would likely affect fewer than 50 jobs across NSW.