Amna Khan, 15, is believed to have run away from her Glenfield house in the early hours of Saturday, November 29.

She phoned her mother later that morning but has not been seen or heard from since.

Macquarie Fields police are worried about her welfare because of her young age.

Amna's family are also concerned and appealing to anyone who knows where she is to contact police.

She is described as being of Indian appearance, about 165 centimetres tall and of a medium build.

Police were particularily interested in hearing from anyone who saw her when she first went missing from her Neva Street house between 4am and 6am.

Anyone with information was urged to contact Crime Stoppers on 1800 333 000.